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The Detroit Zoo is located at the northwest corner of the intersection of Woodward Avenue and 10 Mile Road (I-696) in Royal Oak.

From the east and west, take I-696 to Exit 16 for Woodward Avenue, Main Street, and the Detroit Zoo.

From I-75 north or south, take Exit 61 to I-696 west, Follow I-696 west to Exit 16.

The zoo is entered from either Woodward Avenue or 10 Mile Road; just look for the Detroit Zoo Water Tower.